Google releases Final version of Desktop Search

Wednesday, March 9, 2005Google has today launched the final version of its Google Desktop Search program. Google Desktop is a search engine for Windows which allows the user to search their computer’s files’ contents for a specified phrase, and includes support for many different file types, including audiovisual media, web pages stored in the local cache, e-mail, and various kinds of document files.

In Beta since last Autumn, version 1.0 adds the ability to search PDFs, Netscape/Mozilla/Firefox browser histories, and Thunderbird emails. The software also has an added a plugin facility to allow third-party developers to add support for additional file formats. A registry for a small initial set of plugins is currently available, as well as incentives such as T-shirts and free advertising for developers who submit new plugins.

Competing Windows desktop search products have also been released by Yahoo!, Microsoft, and Copernic. Mac OSX Tiger is planned to offer similar functionality through “Spotlight“, and future Linux distributions are expected to include “Beagle” desktop search.

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13 February

How Hiring Professional Technical Support Professionals Can Benefit Your Business

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If working a regular 9 to 5 job just isn’t for you, starting a small business is a great alternative. While a lot of hard work goes into making a business successful, you will be able to have more freedom when working for yourself. One of the main things you need to focus on when starting out in the world of small business is putting a team in place.

Your new team will need the right technology tools to stay competitive. In most cases, hiring technical support in Dallas professionals is needed. Hiring these tech professionals is beneficial for your business and here are some of the reasons why.

Keeping the Line of Communication Open

Having a functional computer network is about much more than checking Facebook or sending an email. Many businesses use the internet to stay in contact with customers regardless of what time of day it is. If your computer network crashes, these lines of communication will be closed.

This can lead to customers getting angry and may even lead to you losing business. Keeping the lines of communication open is easy when allowing technical support in Dallas professionals help you out. Regardless of what issues your network has, IT professionals will be able to diagnose and fix it quickly.

Optimizing The Network’s Functionality

Dealing with slow download speeds, pop-ups and unstable internet connections while trying to do business can be problematic. Instead of offering up a sub-par network to your team, you can let technical support professionals help you optimize it.

They will be able to implement the latest technology solutions when increasing the functionality of your network. The investment in this kind of support will pay off when workers are able to increase their productivity levels. Neglecting to use an IT professional for this type of work may lead to the competition blowing past you.

12 February

Demonstrators protest Condoleezza Rice’s trip to Australia

Thursday, March 16, 2006

Anti-war demonstrators in Sydney, Australia on Thursday dubbed U.S. Secretary of State Dr Condoleezza Rice a “war criminal” and “murderer.” Two protesters were evicted and five people were arrested during protests against the U.S.-led invasion of Iraq.

Dr Rice, on a three-day trip to Australia, said she understood why people found it hard to be positive about Iraq when all they saw on their television screens was violence.

Soon after Rice began her speech at the University of Sydney’s Conservatorium of Music, two protesters shouted from the rear of the auditorium, “Condoleezza Rice, you are a war criminal,” and “Iraqi blood is on your hands and you cannot wash that blood away.” Standing with their palms towards her, the young man and woman repeated their accusation until security intervened to remove them from the hall.

About 15 minutes into Rice’s address, a third protester appeared at a balcony door, interrupting her speech as she referred to freedom. “What kind of freedom are you talking about? You are a murderer,” said the demonstrator before he was quietly escorted from the hall. “I’m very glad to see that democracy is well and alive here at the university,” she said.

In her speech, Rice sought to justify the U.S. occupation of Iraq, describing Iraqis as now more free. One student asked about abuses committed by U.S. forces at the Abu Ghraib prison in Iraq. She said the abuses had made her “sick to her stomach.” However, she defended Guantanamo Bay, Cuba, where human rights groups say detainees are held in inhumane conditions and in detention flouting international laws.

Before Rice began her speech, about 50 protesters were gathered at the front gates of the Conservatorium. The group were confronted by police on horseback and by police dogs. Police used the horses to charge into the group of activists and push them back, as a police helicopter hovered.

A police spokeswoman said the group was blocking pedestrian access to the building and that police had spent more than 20 minutes warning them to move. The police then moved in and pushed the crowd back 20 metres. Police say five people have been charged with “hindering police in the execution of their duties.”

The “Stop the War Coalition” says Rice is a “war criminal” and is not welcome in Australia. The group’s spokeswoman, Anna Samson, says the protest is one of many planned in the lead-up to the third anniversary of the invasion and occupation of Iraq on March 20.

Paddy Gibson, from the University of Sydney’s Student’s Council, says the protest is in opposition to the Iraq war, and to the use of the University of Sydney’s campus to host Rice, “the most powerful woman in the world,” who they say is a war criminal. “They’re saying, ‘… you’ve got Sydney Uni’s support to stand up and peddle your murderous hate speeches,’ which is what we see it,” he said.

“You’ve got 180,000 people killed, as we said, for no other reason than strategic control of the region’s oil resources. And the anti-Muslim racism that’s been whipped up to justify this war is being felt by Sydney University students,” said Mr Gibson.

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10 February

Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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8 February

How To Choose A Student Travel Company

Submitted by: Steve Brinkman

Presently, high school and middle school teachers are constantly being solicited by student travel companies wanting to take their student group on a tour either within the United States or abroad. In each school system, there are many groups who like to travel including band, chorus, orchestra, dance, science, history, class trips and more. The rush of excitement one faces when planning a tour, though, can overshadow the more important question of Which student travel company is reliable and safe to partner with? In determining which company to choose, one should ask the following questions before making an informed decision:

Is the tour company a member of any association or organization that advocates excellence in student travel?

The student tour operator must be a member of an organization/association that is committed to integrity, honesty, value and service. Associations like the Student & Youth Travel Association (SYTA), the American Bus Association (ABA), the National Tour Association (NTA) and Music Educators National Conference (MENC) are just a few associations that meet these requirements.

What kind of Better Business Bureau (BBB) rating does the company have?

[youtube]http://www.youtube.com/watch?v=7R_65fxHzWk[/youtube]

This is where you can do your homework. Check with the Better Business Bureau to see what kind of overall score the company has. Also, check all reviews and complaints. If there are a lot of complaints or negative reviews, one should probably steer clear of the company in question. On the flip side, if a company has an A+ rating with positive reviews, then this company might warrant a phone call. Moreover, you can check the search engines for reviews and/or complaints as well.

Is the student travel company a full-service company and do they customize trips?

There are many student tour operators who only sell canned trips. Steer clear of this type of operator! They want you to travel using their itinerary, in which they receive hefty incentives from their suppliers for booking a large amount of groups. Unfortunately, most of these companies do not pass these savings and incentives on to you. I suggest choosing a travel company that customizes your trip, your way. Choose a company that provides many options and will meet your curriculum and budgetary needs. Also, make sure the company will plan everything from A to Z providing you with a worry-free trip. This will give you peace-of-mind.

Does the company book reputable vendors?

Choose a company that books only late model motor coaches, books interior corridor hotels, provides security in the hotel, separates male and females on different hotel floors, arranges group dining in reputable restaurants, gives you the option of travel insurance and more. Choose a company that is honest, provides safe and reliable tours and offers specific guidelines on the itinerary, covering all aspects of the trip.

Does the company provide its own tour guide to accompany the group?

The tour guide should accompany the group from the beginning of the trip to the end to oversee all of the arrangements including transportation, accommodations, meals, acquiring attraction tickets and more. A qualified tour guide will help in making one s trip run smoothly.

Does the tour guide know the destination?

For the protection of you and your group, you should choose a company that employs trained guides with certification from schools such as the International Tour Management Institute, a prestigious school specifically accredited for training tour guides. These trained guides not only will know your destination, but are knowledgeable, experienced, friendly and efficient as well.

Overall, do your homework. Ask questions, read brochures, check out websites, call the competing student tour operator companies and find out what to expect from each. By asking the above-mentioned questions, one should be able to narrow down the choices to a few student travel companies. Ask for bids and choose a company that will best suit your travel needs, curriculum requirements and budget. Always make sure you select a safe and reliable company that will customize your trip, your way and provide you with excellent service.

About the Author: For more information, contact: Steve Brinkman; Kaleidoscope Adventures; Phone: 800-774-7337; Fax: 407-345-2890; stevebrinkman.ka@gmail.com;

kaleidoscopeadventures.com

Source:

isnare.com

Permanent Link:

isnare.com/?aid=1059994&ca=Business

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8 February

Wikinews international report: “Anonymous” holds anti-Scientology protests worldwide

Sunday, February 10, 2008

The Internet group Project Chanology today held protests critical of the Church of Scientology. The protests marked what would have been the 49th birthday of Lisa McPherson, who is claimed to be a victim of the Church of Scientology’s practices. Lisa died in 1995 during a running of what Scientologists refer to as an Introspection Rundown, a procedure intended to help Church members deal with a psychotic or deeply traumatic event.

Protests were planned throughout the day in 14 countries and over 50 different cities. The estimation of total protesters world wide for Feb. 10, 2008 is 9,250 people.

Wikinews had correspondents at a number of protest locations to report on the events. This article was updated throughout the day with reports from around the globe.

Contents

  • 1 Location Reports
    • 1.1 Adelaide, Australia
      • 1.1.1 Adelaide Gallery
    • 1.2 Atlanta, Georgia
      • 1.2.1 Atlanta Photo Gallery
    • 1.3 Austin, Texas
      • 1.3.1 Austin Photo Gallery
    • 1.4 Boston, Massachusetts
      • 1.4.1 Boston Photo Gallery
    • 1.5 Brisbane, Australia
      • 1.5.1 Brisbane Gallery
    • 1.6 Brussels, Belgium
      • 1.6.1 Brussels Photo Gallery
    • 1.7 Buffalo, New York
      • 1.7.1 Buffalo Photo Gallery
    • 1.8 Chicago, Illinois
      • 1.8.1 Chicago Photo Gallery
    • 1.9 Clearwater, Florida
    • 1.10 Dallas, Texas
      • 1.10.1 Dallas Photo Gallery
    • 1.11 Edinburgh, Scotland
      • 1.11.1 Edinburgh Photo Gallery
    • 1.12 Honolulu, Hawaii
      • 1.12.1 Honolulu Photo Gallery
    • 1.13 Houston, Texas
    • 1.14 London, England
      • 1.14.1 London Photo Gallery
    • 1.15 Los Angeles, California
      • 1.15.1 Los Angeles Photo Gallery
    • 1.16 Manchester, England
      • 1.16.1 Manchester Photo Gallery
    • 1.17 Melbourne, Australia
      • 1.17.1 Melbourne Photo Gallery
    • 1.18 Minneapolis, Minnesota
    • 1.19 Milwaukee, Wisconsin
      • 1.19.1 Milwaukee Photo Gallery
    • 1.20 New Orleans, Louisiana
      • 1.20.1 New Orleans Photo Gallery
    • 1.21 New York City, New York
      • 1.21.1 New York City Photo Gallery
    • 1.22 Philadelphia, Pennsylvania
    • 1.23 Phoenix, Arizona
      • 1.23.1 Phoenix Photo Gallery
    • 1.24 Pittsburgh, Pennsylvania
      • 1.24.1 Pittsburgh Photo Gallery
    • 1.25 Plymouth, England
      • 1.25.1 Plymouth Photo Gallery
    • 1.26 Portland, Oregon
      • 1.26.1 Portland Photo Gallery
    • 1.27 San Antonio, Texas
    • 1.28 San Diego, California
      • 1.28.1 San Diego Photo Gallery
    • 1.29 Seattle, Washington
      • 1.29.1 Seattle Photo Gallery
    • 1.30 Sydney, Australia
      • 1.30.1 Sydney Photo Gallery
    • 1.31 Toronto, Canada
      • 1.31.1 Toronto Photo Gallery
    • 1.32 Vancouver, Canada
    • 1.33 Vienna, Austria
    • 1.34 Winnipeg, Canada
      • 1.34.1 Winnipeg Photo Gallery
    • 1.35 The Internet
      • 1.35.1 Internet gallery
    • 1.36 Other locations
      • 1.36.1 Stories from other locations
  • 2 Related news
  • 3 Sources
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7 February

Left-wing EU parliament candidates debate in Cardiff

Wednesday, May 27, 2009

Cardiff, Wales —Labour, Plaid Cymru, and No2EU candidates for the Wales seats in the European Parliament met at Cardiff‘s Sandringham Hotel last night for the second of two pre-election hustings debates hosted by Cardiff Trades Union Congress. Cardiff TUC president Katrine Williams moderated as Derek Vaughan of the Labour Party, Jill Evans MEP of Plaid Cymru, and Rob Griffiths of the No2EU coalition, the tops of their respective lists, took questions from an audience of 22 composed largely of socialist activists and trade union members.

Candidates from the Tories, Liberal Democrats, and Green Party were not invited to the evening debate, although the Liberal Democrats did take part in the TUC’s debate earlier in the day. Ms Williams explained that the Liberal Democrats and Tories had been excluded because “we wanted to have candidates more representative of trade unions” but that not inviting the Greens had been “an oversight” due to the less prominent tradition of green politics in Wales. The BNP, UKIP and some minor parties also did not take part.

In opening statements, the three candidates discussed their records and their goals for the European Parliament. Mr Vaughan, leader of Neath Port Talbot County Borough Council, asserted the pro-organised labour credentials of the Labour Party, which has been under fire for several years from the left, and noted that Labour, which currently controls two of Wales’s four seats in the EU Parliament, has brought £1.5 billion to Wales, with a comparable amount to come in the future. Calling the BNP “Nazis” and comparing the British political situation to that in Germany in the 1930s, Vaughan called for the parties of the left to rally behind Labour in order to ensure that the BNP did not obtain any seats in Wales; but he expressed resignation to the likelihood that the BNP would earn a seat in North West England.

Ms Evans, meanwhile, who has been an MEP for ten years, announced her opposition to the pro-privatisation current in the EU and pledged that Plaid would support a new program of public investment and pro-organised labour revisions of EU directives, particularly the Posted Workers Directive.

Mr Griffiths, meanwhile, who is General Secretary of the Communist Party of Britain, took a position urging radical reform of the European Union. The Lisbon Treaty, which he characterised as a re-branding of the European Constitution, would, he argued, enshrine neo-liberal policies in Europe and impose them on its member states in a way that was irreversible — “at least by any constitutional means”. Calling for a “social Europe” as opposed to a “United States of Europe“, Griffiths suggested that the creation of a European Defence Agency and the actions of the European Court of Justice were being used to turn the European Union into a capitalist “empire” akin to the United States.

Discussion of the ongoing UK parliamentary expenses scandal and its implications for MEPs, who draw salaries and expenses considerably higher than Westminster MPs do, dominated the early discussion. The Labour candidate expressed the position that the problems in accountability leading to the scandal had been fixed; his opponents noted that of the parties currently representing Britain in Brussels, only Labour has not yet disclosed their expenses (although Mr Vaughan states that the party will begin to do so soon) and Mr Griffiths furthermore declared that the scandal was part of a wider problem: the corruption of the political system by big business.

On the subject of a common European defence policy the three candidates supported widely differing views. The No2EU candidate stated plainly that he considers Europe not to be threatened, and said that a European defence force would be used for foreign adventures in Afghanistan, Africa, and elsewhere in the developing world while at the same time building up the armaments industry in Europe. Ms Evans, meanwhile, argued that the proper role of a common EU force would be as a “civil force” supporting conflict prevention and conflict resolution operations, and also called for the abolition of NATO. Mr Vaughan finished the second round of questioning arguing that a common European armed force should be an alternative to the “US-dominated” NATO, but also stated the importance of bilateral alliances in building up a common European defence force, citing the Franco-German Brigade of the Eurocorps as an example.

Debate ended on the contentious question of MEP salaries, with one member of the audience challenging the three candidates to pledge to accept a wage, if they won, equal to the average wage of their constituents. Ms Evans agreed that the set wage, currently £63,000 rising to £73,000 in 2010, was “too high”, but would not commit to a so-called “worker’s wage”, under heavy criticism from the audience. Mr Vaughan, following, called it “not fair” to ask MEPs to take such a pledge but asserted “I have never been motivated by money” and finished his part in the debate with a call to elect more left-wing socialist MEPs. Mr Griffiths, whose No2EU coalition has made a worker’s wage for MEPs part of their election manifesto, readily pledged to hold to a living wage, albeit not necessarily one equal to the average wage of his constituents, and described some of the difficulties associated with refusing an EU salary, noting that initially No2EU had proposed that its MEPs should draw no salary and claim no expenses from Europe but the coalition’s legal advisors had said that to do so would endanger the status of any of its members as MEPs.

Voting for the European Parliament elections in the United Kingdom takes place June 4.

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7 February

Get Expertly Designed Banners In Rancho Cucamonga, Ca

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It might be that you’re getting ready for the grand opening of your brand-new business or restaurant. It might be that you’ve done extensive remodeling to your place of business and are actually looking into a grand reopening to get people excited about your product. It might be that you’re looking to advertise not for a business per se, but a club or cause or other social activity. Whatever the case may be, you’re looking to raise awareness of your cause or brand.

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Graphic design is one of the most popular degrees for college students today and with good reason. Shirts, bags, and other printed goods, including banners, look incredibly professional. With the tools created by this field, and put to use by those that specialize in it, you’ll be able to get an incredible banner faster and with more options than ever before. Graphic design for computer-based banner design schemes allows creators to both be more precise when designing items and make mass production of a particular design that much easier. This is good news for anyone looking for high-quality, quickly-manufactured banners to promote their cause or business.

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7 February

Kordia’s annual report shows increase in profit

Friday, October 12, 2007

New Zealand state-owned enterprise (SOE), Kordia published its annual report a few days ago for the financial year ending June 30, 2007.

Formerly known as Broadcast Communications Ltd (BCL) prior to the name change in November 2006, the Crown-owned company offers contracting, consulting, and networking services. They operate a national communication network and provides network feeds and broadcast services for the major television and radio networks in New Zealand.

The annual report shows Kordia Group Limited’s net profit, after tax, at NZ$11.9 million, the 2006 result was $9.8 million. Revenue was up from $201 million in the 2006 financial year to $264 million this year; a 31% increase. Chairman of Kordia, Wayne Brown, described this financial year as “solid achievement” while being “on track to record further growth in the exciting fields in which it operates.”

These increases is despite the major acquisition of Orcon Internet Limited, an ISP (Internet service provider). Kordia will use Orcon, acquired on 2 July, 2007, to invest and deliver the possibilities of the current progress of local loop unbundling, new Wi-Fi zones, and WiMAX technology. CEO of Kordia, Geoff Hunt, said, “Orcon will soon offer a complete range of Voice over IP products”. Orcon is being operated at arms-length to the rest of the company.

Other areas where Kordia is advancing itself is mobile television transmission where they are already prepared to start services once content providers have been secured. Hunt said, “Spectrum is available, so all we need are the content providers and some good consumer demand. Then we’ll be ready to roll.”

Kordia is also immersing itself further in the television sector as well as its mobile television service. Other advances includes New Zealand’s new digital television service, Freeview with it set to start terrestrial transmission next year.

Parliament TV also began this year in July. All House proceedings are available via the Parliament website and a broadcast quality feed is provided to all broadcasters, with full coverage being televised by Freeview and Sky Network Television. The manager of Kordia’s Transmission Control Centre, Merv Brooks, said, “This is another example of people and technology coming together to deliver a truly unique product to New Zealanders.”

Being a SOE, Kordia is required to give the Government a dividend. The Government will receive a total dividend of $8.4 million; $6.8 million in 2006. A $3 million dividend had already been received by the Government so a payment of only $5.4 million was made.

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5 February

Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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5 February